Sale!

GW 501516

$59.99 $49.99

20mg/mL.

30mL.

Description

Buy GW 501516

20mg/mL – 30mL Bottle.

Cardarine for Sale. Buy GW 501516. PPARδ Agonist. [>99.8% Purity].

Inactive Ingredients: Solvent Matrix. Preservative.

GW 501516 (Cardarine) is a PPARδ receptor agonist, also known as Endurobol. Based on available research, GW 501516 (Cardarine) has shown to accelerate metabolic rate, and subsequently, the burning of body fat. GW 501516 (Cardarine) was created via a collaboration between Ligand Pharmaceuticals GlaxoSmithKline in the 1990s,  initially in clinical development for the treatment of cardiovascular and metabolic diseases. GW 501516 (Cardarine) binds to and activates the peroxisome proliferator activator receptor delta (PPAR-delta). A variety of PPAR-delta is inside the skeletal muscle tissues, and activation of this receptor affects genes related to improved metabolic function and increased physical performance.

In currently available rat studies, binding of GW 501516 (Cardarine) to PPARδ promotes the recruitment of the coactivator PGC-1α. This PPARδ and co-activator complex, when active, upregulates the expression of proteins involved in the process of energy expenditure. Similar studies performed in rats showed that GW 501516 (Cardarine) caused an increase in fatty acid metabolism in skeletal muscle tissue. Regarding improvement in metabolic parameters, GW 501516 (Cardarine) also showed evidence of protection against diet-induced obesity and type II diabetes. When further studies were performed in primates,  GW 501516 had shown to increase HDL (high-density lipoprotein) and simultaneously lower VLDL (very-low-density lipoprotein)

Buy GW 501516 (Cardarine) from ELV Bioscience.

VIEW OTHER PRODUCTS


CONTACT US for bulk quantities.

Cardarine for Sale is laboratory use and research purposes only.

ELV Bioscience Data Sheet: Cardarine (GW501516)

Certificate of Analysis (CoA)

Batch: EGW26103

Product Name: GW501516

CAS Number: 317318-70-0

Chemical Name: {4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid

Physical and Chemical Properties

Chemical Formula: C21H18F3N03S

Synonyms: GW501516, GW-501516, Cardarine, Endurobol, GSK-516

Molecular Weight: 453.494 g/mol

Analytical Data

HPLC: Shows Min 99.86% Purity

H-NMR: Consistent with structure.

Product Information

Peroxisome proliferator-activated receptor 8 (PPAR8) stimulation or over-expression in adipocytes leads to increased fatty acid oxidation, improved exercise tolerance, and resistance to obesity. IGW 501516 is the fust highly selective syntl1etic PPAR8 agonist available. GW 501516 binds to human PPAR8 with an IC50 value of 1 nM and is at least 100-fold selective fo1 PPAR8 compared to PPARa and PPARy .2 Inobese primates, GW 501516 increases high-density lipoprotein cholesterol and apolipoprotein A- 1 specific reverse cholesterol transpo11.3 GW 501516 is, therefore, a model compound for a new type of obesity therapeutic, as well as a selective pharmacological tool for understanding lipid metabolism.

Additional information

Weight 4 oz
Class

PPARδ receptor agonist

CAS

317318-70-0

Molecular Weight

453.494 g/mol

Chemical Formula

C21H18F3NO3S2

Chemical Name

{4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid

Synonyms

GW501516, GW-501516, Cardarine, Endurobol, GSK-516

Reviews

There are no reviews yet.

Be the first to review “GW 501516”

Your email address will not be published. Required fields are marked *