20mg/mL – 30mL Bottle.
Buy GW501516. PPARδ Agonist. [>99.8% Purity].
Inactive Ingredients: Solvent Matrix. Preservative.
GW501516 (Cardarine) is a PPARδ receptor agonist, also known as Endurobol. Based on available research, GW501516 (Cardarine) has shown to accelerate metabolic rate, and subsequently, the burning of body fat. GW501516 (Cardarine) was created via collaboration between Ligand Pharmaceuticals GlaxoSmithKline the in 1990’s, initially in clinical development for the treatment of cardiovascular and metabolic diseases. GW501516 (Cardarine) binds to and activates the peroxisome proliferator activator receptor delta (PPAR-delta). A variety of PPAR-delta is inside the skeletal muscle tissues, and activation of this receptor affects genes related to improved metabolic function and increased physical performance.
In currently available rat studies, binding of GW501516 (Cardarine) to PPARδ promotes recruitment of the coactivator PGC-1α. This PPARδ and co-activator complex, when active, upregulates the expression of proteins involved in the process of energy expenditure. Similar studies performed in rats showed that GW501516 (Cardarine) caused an increase in fatty acid metabolism in skeletal muscle tissue. Regarding improvement in metabolic parameters, GW501516 (Cardarine) also showed evidence of protection against diet-induced obesity and type II diabetes. When further studies were performed in primates, GW501516 had shown to increase HDL (high-density lipoprotein) and simultaneously lower VLDL (very-low-density lipoprotein)
Buy GW501516 (Cardarine) from ELV Bioscience.
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